| Betika Jackpot |  | 11 Dec | 16:30 EAT | Anderlecht vs Club Brugge KV | 0-0 | 1 |
| Betika Jackpot | | 11 Dec | 17:00 EAT | Le Mont vs Aarau | 0-0 | X2 |
| Betika Jackpot | | 11 Dec | 17:00 EAT | Wohlen vs Schaffhausen | 4-0 | X2 |
| Betika Jackpot | | 11 Dec | 17:00 EAT | Palermo vs Chievo | 0-2 | X |
| Betika Jackpot | | 11 Dec | 17:00 EAT | Bologna vs Empoli | 0-0 | 1 |
| Betika Jackpot | | 11 Dec | 17:15 EAT | Manchester United vs Tottenham | 1-0 | 1 |
| Betika Jackpot | | 11 Dec | 18:15 EAT | Celta Vigo vs Sevilla | 0-3 | 1 |
| Betika Jackpot | | 11 Dec | 19:00 EAT | St Etienne vs Guingamp | 1-0 | 1 |
| Betika Jackpot | | 11 Dec | 19:30 EAT | Schalke vs Bayer Leverkusen | 0-1 | 1 |
| Betika Jackpot | | 11 Dec | 19:30 EAT | Brescia vs Novara | 0-0 | X2 |
| Betika Jackpot | | 11 Dec | 21:00 EAT | Benfica vs Sporting | 2-1 | 1X |
| Betika Jackpot | | 11 Dec | 22:00 EAT | Waasland-Beveren vs Genk | Postponed | 2 |
| Betika Jackpot | | 11 Dec | 22:45 EAT | Betis vs Ath Bilbao | 1-0 | 1X |
