| Home – Away | Score | FT | UO | ||
|---|---|---|---|---|---|
 | Horsens vs Sonderjyske 08 Dec – 21:00 EAT – Denmark – Superliga | 2-1 | 2 | O | |
 | Waasland-Beveren vs St. Liege 08 Dec – 22:30 EAT – Belgium – Jupiler League | 3-1 | 2 | U | |
| KSV Roeselare vs Cercle Brugge KSV 08 Dec – 22:30 EAT – Belgium – Proximus League | 0-3 | 2 | U | |
 | VfB Stuttgart vs Bayer Leverkusen 08 Dec – 22:30 EAT – Germany – Bundesliga | 0-2 | 2 | O | |
 | Gornik Z. vs Lechia Gdansk 08 Dec – 22:30 EAT – Poland – Ekstraklasa | 1-1 | 1 | O | |
 | Barcelona B vs Gijon 08 Dec – 23:00 EAT – Spain – LaLiga2 | 2-1 | 1 | O | |
| Alaves vs Las Palmas 08 Dec – 23:00 EAT – Spain – LaLiga | 2-0 | 1 | O |