| Home – Away | Score | #1 | #2 | #3 | ||
|---|---|---|---|---|---|---|
| 1 – Odd Grenland vs Molde 16/12/2020 – 20:00 GMT+3 – Norway – Eliteserien | 1-4 | 2 | 1 | 2 | ||
| 2 – Derby vs Swansea 16/12/2020 – 20:30 GMT+3 – England – Championship | 2-0 | 1 | 2 | 2 | ||
| 3 – Schalke vs Freiburg 16/12/2020 – 20:30 GMT+3 – Germany – Bundesliga | 0-2 | 2 | 2 | 2 | ||
| 4 – Holstein Kiel vs Nurnberg 16/12/2020 – 20:30 GMT+3 – Germany – 2. Bundesliga | 1-0 | 1 | 1 | 1 | ||
| 5 – Wurzburger Kickers vs St. Pauli 16/12/2020 – 20:30 GMT+3 – Germany – 2. Bundesliga | Postp | 2 | 2 | 2 | ||
| 6 – Reims vs Nantes 16/12/2020 – 21:00 GMT+3 – France – Ligue 1 | 3-2 | X | X | X | ||
| 7 – Bielefeld vs Augsburg 16/12/2020 – 22:30 GMT+3 – Germany – Bundesliga | 0-1 | 1 | 1 | 1 | ||
| 8 – Fiorentina vs Sassuolo 16/12/2020 – 22:45 GMT+3 – Italy – Serie A | 1-1 | 1 | 1 | X | ||
| 9 – Parma vs Cagliari 16/12/2020 – 22:45 GMT+3 – Italy – Serie A | 0-0 | X | X | X | ||
| 10 – Fulham vs Brighton 16/12/2020 – 23:00 GMT+3 – England – Premier League | 0-0 | 1 | 2 | 1 | ||
| 11 – Coventry vs Huddersfield 16/12/2020 – 23:00 GMT+3 – England – Championship | 0-0 | 1 | 2 | 1 | ||
| 12 – Reading vs Norwich 16/12/2020 – 23:00 GMT+3 – England – Championship | 1-2 | 2 | 2 | 1 | ||
| 13 – Rennes vs Marseille 16/12/2020 – 23:00 GMT+3 – France – Ligue 1 | 2-1 | 1 | X | X |